David Benjamin Goldstein

missing portrait

Adjunct Professor in the Department of Molecular Genetics and Microbiology

External address: 
P and S 630 West 168th Street, Suite 11 101, New York, NY 10032
Internal office address: 
268 CARL, Box 3054, Durham, NC 27710
Phone: 
(212) 305-0932

Education

  • Ph.D., Stanford University 1994

Altman, RB, Flockhart, D, Goldstein, DB, Altman, RB, Flockhart, D, and Goldstein, DB. Principles of pharmacogenetics and pharmacogenomicsPrinciples of pharmacogenetics and pharmacogenomics (PublishedPublished). January 1, 2012. Full Text

Altman, RB, Flockhart, D, and Goldstein, DB. "Introduction." xi-xii. January 1, 2012. Full Text

Walley, NM, Nicoletti, P, and Goldstein, DB. "Pharmacogenetics." In Vogel and Motulsky's Human Genetics: Problems and Approaches (Fourth Edition), 635-647. January 1, 2010. Full Text

Gelfman, S, Wang, Q, McSweeney, KM, Ren, Z, La Carpia, F, Halvorsen, M, Schoch, K, Ratzon, F, Heinzen, EL, Boland, MJ, Petrovski, S, and Goldstein, DB. "Annotating pathogenic non-coding variants in genic regions." Nature communications 8, no. 1 (August 9, 2017): 236-. Full Text

Black, HA, Leighton, DJ, Cleary, EM, Rose, E, Stephenson, L, Colville, S, Ross, D, Warner, J, Porteous, M, Gorrie, GH, Swingler, R, Goldstein, D, Harms, MB, Connick, P, Pal, S, Aitman, TJ, and Chandran, S. "Corrigendum to “Genetic epidemiology of motor neuron disease-associated variants in the Scottish population.” [Neurobiol. Aging 51 (2017) 178.e11–178.e20]." Neurobiology of Aging 56 (August 2017): 214-214. Full Text

Petrovski, S, Todd, JL, Durheim, MT, Wang, Q, Chien, JW, Kelly, FL, Frankel, C, Mebane, CM, Ren, Z, Bridgers, J, Urban, TJ, Malone, CD, Finlen Copeland, A, Brinkley, C, Allen, AS, O'Riordan, T, McHutchison, JG, Palmer, SM, and Goldstein, DB. "An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis." American journal of respiratory and critical care medicine 196, no. 1 (July 2017): 82-93. Full Text

Epi4K Consortium, , EuroEPINOMICS-RES Consortium, , and Epilepsy Phenome Genome Project, . "Application of rare variant transmission disequilibrium tests to epileptic encephalopathy trio sequence data." European journal of human genetics : EJHG 25, no. 7 (June 2017): 894-899. Full Text

Black, HA, Leighton, DJ, Cleary, EM, Rose, E, Stephenson, L, Colville, S, Ross, D, Warner, J, Porteous, M, Gorrie, GH, Swingler, R, Goldstein, D, Harms, MB, Connick, P, Pal, S, Aitman, TJ, and Chandran, S. "Genetic epidemiology of motor neuron disease-associated variants in the Scottish population." Neurobiology of Aging 51 (March 2017): 178.e11-178.e20. Full Text

Schoch, K, Meng, L, Szelinger, S, Bearden, DR, Stray-Pedersen, A, Busk, OL, Stong, N, Liston, E, Cohn, RD, Scaglia, F, Rosenfeld, JA, Tarpinian, J, Skraban, CM, Deardorff, MA, Friedman, JN, Akdemir, ZC, Walley, N, Mikati, MA, Kranz, PG, Jasien, J, McConkie-Rosell, A, McDonald, M, Wechsler, SB, Freemark, M, Kansagra, S, Freedman, S, Bali, D, Millan, F, Bale, S, Nelson, SF, Lee, H, Dorrani, N, UCLA Clinical Genomics Center, , Undiagnosed Diseases Network, , Goldstein, DB, Xiao, R, and Yang, Y et al. "A Recurrent De Novo Variant in NACC1 Causes a Syndrome Characterized by Infantile Epilepsy, Cataracts, and Profound Developmental Delay." American journal of human genetics 100, no. 2 (February 2017): 343-351. Full Text

Epi4K consortium, , and Epilepsy Phenome/Genome Project, . "Ultra-rare genetic variation in common epilepsies: a case-control sequencing study." The Lancet. Neurology 16, no. 2 (February 2017): 135-143. Full Text

Gussow, AB, Copeland, BR, Dhindsa, RS, Wang, Q, Petrovski, S, Majoros, WH, Allen, AS, and Goldstein, DB. "Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics." PloS one 12, no. 8 (January 2017): e0181604-. Full Text

Shashi, V, Pena, LDM, Kim, K, Burton, B, Hempel, M, Schoch, K, Walkiewicz, M, McLaughlin, HM, Cho, M, Stong, N, Hickey, SE, Shuss, CM, Undiagnosed Diseases Network, , Freemark, MS, Bellet, JS, Keels, MA, Bonner, MJ, El-Dairi, M, Butler, M, Kranz, PG, Stumpel, CTRM, Klinkenberg, S, Oberndorff, K, Alawi, M, Santer, R, Petrovski, S, Kuismin, O, Korpi-Heikkilä, S, Pietilainen, O, Aarno, P, Kurki, MI, Hoischen, A, Need, AC, Goldstein, DB, and Kortüm, F. "De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype." American journal of human genetics 100, no. 1 (January 2017): 179-. Full Text

Appenzeller, S, Balling, R, Barisic, N, Baulac, S, Caglayan, H, Craiu, D, De Jonghe, P, Depienne, C, Dimova, P, Djémié, T, Gormley, P, Guerrini, R, Helbig, I, Hjalgrim, H, Hoffman-Zacharska, D, Jähn, J, Klein, KM, Koeleman, B, Komarek, V, Krause, R, Kuhlenbäumer, G, Leguern, E, Lehesjoki, A-E, Lemke, JR, Lerche, H, Linnankivi, T, Marini, C, May, P, Møller, RS, Muhle, H, Pal, D, Palotie, A, Pendziwiat, M, Robbiano, A, Roelens, F, Rosenow, F, Selmer, K, Serratosa, JM, Sisodiya, S, and Stephani, U et al. "De Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies." The American Journal of Human Genetics 100, no. 1 (January 2017): 179-179. Full Text

Pages

Hafler, DA, Rao, A, Goodnow, CC, Abbas, AK, Wakeland, EK, Behrens, TW, Goldstein, DB, Kere, J, Cookson, W, Seed, B, Lindgren, C, Bowcock, A, Kuchroo, VK, Vyse, TJ, Wijmenga, C, and Wicker, LS. "Discussion." December 1, 2005.

Kertai, MD, Li, Y-W, Li, Y-J, Shah, SH, Kraus, WE, Fontes, ML, Stafford-Smith, M, Newman, MF, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers." Circulation. Cardiovascular genetics 7, no. 5 (October 2014): 625-633. Full Text

Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health (Preceptor). 2009 to 2020

Pathways From Maltreatment to Substance Abuse awarded by National Institutes of Health (Collaborator). 2010 to 2016

Statistical Models to Investigate Long-Distance QTL Transcription Regulation awarded by National Institutes of Health (Collaborator). 2011 to 2015

Multidisciplinary Neonatal Training Grant awarded by National Institutes of Health (Mentor). 2010 to 2015

Identifying the Causes of Primary immunodeficiency through Next Generation Sequencing awarded by Baxter Healthcare Corporation (Collaborator). 2014 to 2015

Exploratory genomic investigations of mesial temporal lobe epilepsy awarded by National Institutes of Health (Co Investigator). 2012 to 2015

1/3-Identifying regulatory mutations that influence neuropsychiatric disease awarded by National Institutes of Health (Principal Investigator). 2014

Epilepsy Genetics Repository awarded by Citizens United for Research in Epilepsy (Principal Investigator). 2014

Unravelling the genetics of the common epilepsies using discordant monozygotic twins awarded by University of Melbourne (Principal Investigator). 2014

Identifying de novo mutations causing OCD in trios by whole exome sequencing awarded by National Institutes of Health (Principal Investigator). 2013 to 2014

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