David Benjamin Goldstein

missing portrait

Adjunct Professor in the Department of Molecular Genetics and Microbiology

External address: 
P and S 630 West 168th Street, Suite 11 101, New York, NY 10032
Internal office address: 
268 CARL, Box 3054, Durham, NC 27710
Phone: 
(212) 305-0932

Education

  • Ph.D., Stanford University 1994

Altman, RB, Flockhart, D, Goldstein, DB, Altman, RB, Flockhart, D, and Goldstein, DB. Principles of pharmacogenetics and pharmacogenomicsPrinciples of pharmacogenetics and pharmacogenomics (PublishedPublished). January 1, 2012. Full Text

Dhindsa, RS, Lowenstein, DH, and Goldstein, DB. "Molecular Architecture and Neurobiology of the Epilepsies." In Genomics, Circuits, and Pathways in Clinical Neuropsychiatry, 601-617. June 21, 2016. Full Text

Altman, RB, Flockhart, D, and Goldstein, DB. "Introduction." xi-xii. January 1, 2012. Full Text

Walley, NM, Nicoletti, P, and Goldstein, DB. "Pharmacogenetics." In Vogel and Motulsky's Human Genetics: Problems and Approaches (Fourth Edition), 635-647. January 1, 2010. Full Text

Sanna-Cherchi, S, Khan, K, Westland, R, Krithivasan, P, Fievet, L, Rasouly, HM, Ionita-Laza, I, Capone, VP, Fasel, DA, Kiryluk, K, Kamalakaran, S, Bodria, M, Otto, EA, Sampson, MG, Gillies, CE, Vega-Warner, V, Vukojevic, K, Pediaditakis, I, Makar, GS, Mitrotti, A, Verbitsky, M, Martino, J, Liu, Q, Na, YJ, Goj, V, Ardissino, G, Gigante, M, Gesualdo, L, Janezcko, M, Zaniew, M, Mendelsohn, CL, Shril, S, Hildebrandt, F, van Wijk, JAE, Arapovic, A, Saraga, M, Allegri, L, Izzi, C, and Scolari, F et al. "Erratum: Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations (The American Journal of Human Genetics (2017) 101(5) (789–802) (S0002929717303877) (10.1016/j.ajhg.2017.09.018))." American Journal of Human Genetics 101, no. 6 (December 7, 2017): 1034-. Full Text

Sanders, SJ, Neale, BM, Huang, H, Werling, DM, An, JY, Dong, S, Abecasis, G, Arguello, PA, Blangero, J, Boehnke, M, Daly, MJ, Eggan, K, Geschwind, DH, Glahn, DC, Goldstein, DB, Gur, RE, Handsaker, RE, McCarroll, SA, Ophoff, RA, Palotie, A, Pato, CN, Sabatti, C, State, MW, Jeremy Willsey, A, Hyman, SE, Addington, AM, Lehner, T, and Freimer, NB. "Whole genome sequencing in psychiatric disorders: The WGSPD consortium." Nature Neuroscience 20, no. 12 (December 1, 2017): 1661-1668. (Review) Full Text

Rotemberg, V, Garzon, M, Lauren, C, Iglesias, A, Brachio, SS, Aggarwal, V, Stong, N, Goldstein, DB, and Diacovo, T. "A Novel Mutation in Junctional Plakoglobin Causing Lethal Congenital Epidermolysis Bullosa." The Journal of pediatrics 191 (December 2017): 266-269.e1. Full Text

Zhu, X, Padmanabhan, R, Copeland, B, Bridgers, J, Ren, Z, Kamalakaran, S, O'Driscoll-Collins, A, Berkovic, SF, Scheffer, IE, Poduri, A, Mei, D, Guerrini, R, Lowenstein, DH, Allen, AS, Heinzen, EL, and Goldstein, DB. "A case-control collapsing analysis identifies epilepsy genes implicated in trio sequencing studies focused on de novo mutations." PLoS genetics 13, no. 11 (November 29, 2017): e1007104-. Full Text

Sanna-Cherchi, S, Khan, K, Westland, R, Krithivasan, P, Fievet, L, Rasouly, HM, Ionita-Laza, I, Capone, VP, Fasel, DA, Kiryluk, K, Kamalakaran, S, Bodria, M, Otto, EA, Sampson, MG, Gillies, CE, Vega-Warner, V, Vukojevic, K, Pediaditakis, I, Makar, GS, Mitrotti, A, Verbitsky, M, Martino, J, Liu, Q, Na, Y-J, Goj, V, Ardissino, G, Gigante, M, Gesualdo, L, Janezcko, M, Zaniew, M, Mendelsohn, CL, Shril, S, Hildebrandt, F, van Wijk, JAE, Arapovic, A, Saraga, M, Allegri, L, Izzi, C, and Scolari, F et al. "Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations." American journal of human genetics 101, no. 5 (November 2017): 789-802. Full Text

McLaren, PJ, Pulit, SL, Gurdasani, D, Bartha, I, Shea, PR, Pomilla, C, Gupta, N, Gkrania-Klotsas, E, Young, EH, Bannert, N, Del Amo, J, Gill, MJ, Gilmour, J, Kellam, P, Kelleher, AD, Sönnerborg, A, Zangerle, R, Post, FA, Fisher, M, Haas, DW, Walker, BD, Porter, K, Goldstein, DB, Sandhu, MS, de Bakker, PIW, and Fellay, J. "Evaluating the Impact of Functional Genetic Variation on HIV-1 Control." The Journal of infectious diseases 216, no. 9 (November 2017): 1063-1069. Full Text

Myers, CT, Stong, N, Mountier, EI, Helbig, KL, Freytag, S, Sullivan, JE, Ben Zeev, B, Nissenkorn, A, Tzadok, M, Heimer, G, Shinde, DN, Rezazadeh, A, Regan, BM, Oliver, KL, Ernst, ME, Lippa, NC, Mulhern, MS, Ren, Z, Poduri, A, Andrade, DM, Bird, LM, Bahlo, M, Berkovic, SF, Lowenstein, DH, Scheffer, IE, Sadleir, LG, Goldstein, DB, Mefford, HC, and Heinzen, EL. "De Novo Mutations in PPP3CA Cause Severe Neurodevelopmental Disease with Seizures." American journal of human genetics 101, no. 4 (October 2017): 516-524. Full Text

Wangler, MF, Yamamoto, S, Chao, H-T, Posey, JE, Westerfield, M, Postlethwait, J, Members of the Undiagnosed Diseases Network (UDN), , Hieter, P, Boycott, KM, Campeau, PM, and Bellen, HJ. "Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research." Genetics 207, no. 1 (September 2017): 9-27. (Review) Full Text

Gelfman, S, Wang, Q, McSweeney, KM, Ren, Z, La Carpia, F, Halvorsen, M, Schoch, K, Ratzon, F, Heinzen, EL, Boland, MJ, Petrovski, S, and Goldstein, DB. "Annotating pathogenic non-coding variants in genic regions." Nature communications 8, no. 1 (August 9, 2017): 236-. Full Text

Black, HA, Leighton, DJ, Cleary, EM, Rose, E, Stephenson, L, Colville, S, Ross, D, Warner, J, Porteous, M, Gorrie, GH, Swingler, R, Goldstein, D, Harms, MB, Connick, P, Pal, S, Aitman, TJ, and Chandran, S. "Corrigendum to “Genetic epidemiology of motor neuron disease-associated variants in the Scottish population.” [Neurobiol. Aging 51 (2017) 178.e11–178.e20]." Neurobiology of Aging 56 (August 2017): 214-214. Full Text

Pages

McLaren, PJ, Coulonges, C, Bartha, I, Lenz, TL, Deutsch, AJ, Bashirova, A, Buchbinder, S, Carrington, MN, Cossarizza, A, Dalmau, J, De Luca, A, Goedert, JJ, Gurdasani, D, Haas, DW, Herbeck, JT, Johnson, EO, Kirk, GD, Lambotte, O, Luo, M, Mallal, S, van Manen, D, Martinez-Picado, J, Meyer, L, Miro, JM, Mullins, JI, Obel, N, Poli, G, Sandhu, MS, Schuitemaker, H, Shea, PR, Theodorou, I, Walker, BD, Weintrob, AC, Winkler, CA, Wolinsky, SM, Raychaudhuri, S, Goldstein, DB, Telenti, A, and de Bakker, PIW et al. "Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load." November 9, 2015. Full Text

Wilson Sayres, MA, Brookes, AJ, Chanock, SJ, Cheung, VG, Goldstein, DB, Jin, L, and Kwok, P-Y. "HGV2011: personalized genomic medicine meets the incidentalome." March 2012. Full Text

Hafler, DA, Rao, A, Goodnow, CC, Abbas, AK, Wakeland, EK, Behrens, TW, Goldstein, DB, Kere, J, Cookson, W, Seed, B, Lindgren, C, Bowcock, A, Kuchroo, VK, Vyse, TJ, Wijmenga, C, and Wicker, LS. "Discussion." December 1, 2005.

Kertai, MD, Li, Y-W, Li, Y-J, Shah, SH, Kraus, WE, Fontes, ML, Stafford-Smith, M, Newman, MF, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers." Circulation. Cardiovascular genetics 7, no. 5 (October 2014): 625-633. Full Text

Selected Grants

Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health (Preceptor). 2009 to 2020

Pathways From Maltreatment to Substance Abuse awarded by National Institutes of Health (Collaborator). 2010 to 2016

Statistical Models to Investigate Long-Distance QTL Transcription Regulation awarded by National Institutes of Health (Collaborator). 2011 to 2015

Multidisciplinary Neonatal Training Grant awarded by National Institutes of Health (Mentor). 2010 to 2015

Identifying the Causes of Primary immunodeficiency through Next Generation Sequencing awarded by Baxter Healthcare Corporation (Collaborator). 2014 to 2015

Exploratory genomic investigations of mesial temporal lobe epilepsy awarded by National Institutes of Health (Co Investigator). 2012 to 2015

1/3-Identifying regulatory mutations that influence neuropsychiatric disease awarded by National Institutes of Health (Principal Investigator). 2014

Epilepsy Genetics Repository awarded by Citizens United for Research in Epilepsy (Principal Investigator). 2014

Unravelling the genetics of the common epilepsies using discordant monozygotic twins awarded by University of Melbourne (Principal Investigator). 2014

Identifying de novo mutations causing OCD in trios by whole exome sequencing awarded by National Institutes of Health (Principal Investigator). 2013 to 2014

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